X chromosome and suicide

X Chromosome Inactivation in Opioid Addicted Women

Introduction: X chromosome inactivation (XCI) is a process during which one of the two X chromosomes in female human is silenced leading to equal gene expression with males who have only one X chromosome. Here we have investigated XCI ratio in females with opioid addiction to see whether XCI skewness in women could be a risk factor for opioid addiction. Methods: 30 adult females meeting DS...

x chromosome inactivation

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Immunoglobulins and the X-chromosome.

Serum levels of immunoglobulins (Ig) G, M, and A were determined in 28 women with an additional X-chromosome (XXX), and in equal numbers of age-matched normal women and men. Mean IgM levels were found to be highest in the XXX group, intermediate in normal women, and lowest in men; these differences were statistically significant. Mean IgM values obtained from seven XXY and three XXXY cases were...

X Chromosome: Expression and Escape

Although there are some obvious differences between the X chromosome and the autosomes—such as the X chromosome being present in only one copy in males— the two types of chromosome are remarkably similar in their cytological appearance and gene density [1]. Genomic and transcriptomic studies of Drosophila, however, have revealed two major differences in gene content between the X chromosome and...

X-Chromosome Complement and Estrogen